Heart Disease

A leading menu of blood tests to assist in the diagnosis of coronary heart disease

CKMB is an enzyme mostly found mainly in the heart muscle. It is one of three separate forms of the enzyme creatine kinase (CK). The level of this enzyme rises when there is any disease or damage to heart muscle cells. CK-MB testing helps determine if a heart attack has occurred, and to monitor the effectiveness of certain clot-busting medications (thrombolytic).

The troponin family of proteins is found in the heart and in other muscles, serving to help muscles contract, and is released into the bloodstream when a heart attack occurs. Troponin testing measures the levels of troponin in the bloodstream, and is usually performed in conjunction with tests such as CK, CKMB, and myoglobin to determine if a heart attack is suspected, or has already occurred.

An amino acid produced as the body metabolizes protein. Homocysteine at high levels may damage arterial vessels thereby increasing the risk of cardiovascular disease.

Myoglobin is a protein found in the heart and other muscles throughout the body. This protein traps oxygen in muscles to allow the muscle cells to function properly, and is released into the bloodstream when the heart or other muscles are injured. Myoglobin testing helps determine if damage to the heart has occurred, specifically in conjunction with other tests (such as CKMB or troponin) to tell whether the damage was to heart or to other muscles.

High levels of this protein in the bloodstream can also occur in surgery, accidents, seizures, as well as other muscle-related trauma.
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